ALLERGIC REACTION TO AN AMIDE LOCAL ANAESTHETIC

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Allergic reaction to an amide local anaesthetic.

A 67-yr-old female patient gave a history of allergy to lignocaine. When she was challenge-tested with the intradermal injection of 0.5% bupivacaine 0.2ml she had a systemic reaction. This reaction was accompanied by a decrease in the concentration of complement C4 in the plasma, which indicated that the reaction was immunologically-mediated. This is the first report of allergy to a local anaes...

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Immediate- and delayed-type allergic reactions to amide local anesthetics: clinical features and skin testing.

PURPOSE Amide type local anesthetic agents are among the most commonly used drugs in medicine. Several adverse drug reactions (ADRs) have been previously described with their use. Among them, allergic reactions are considered rare. The aim of this study was to describe the main characteristics of ADRs induced by amide type local anesthetic drugs. METHODS We studied reports recorded in the Fre...

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Awareness of Anaphylaxis Reaction to Local Anaesthetic Drugs among Dental Students- a Cross Sectional Study

Aim: The aim of the study was to determinee the knowledge of dental students about signs, symptoms and management of anaphylaxis reaction to local anaesthetic drugs. Materials and Method: The study was designed with a pretested interviewer questionnaire containing 14 questions related to anaphylaxis to local anaesthesia in a private dental college. The interns and the postgraduates were randoml...

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Investigation of allergic and hypersensitivity reactions to anaesthetic agents.

Some three million general anaesthetics are administered annually in the United Kingdom, for a variety of surgical procedures. It is inevitable that untoward reactions will occur, but it is the incidence of the reactions which gives cause for concern. Lunn and Mushin (1982) described almost 300 deaths per year totally attributable to anaesthesia and a much larger number, 1800 deaths, in which a...

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Delayed-type hypersensitivity to amide local anesthetics.

We present a 54-year-old woman who suffered eczematous eruptions on her face after the administration of lidocaine and mepivacaine for dental surgeries. Patch tests showed delayed-type-hypersensitivity to the amide local anesthetics lidocaine and mepivacaine with cross reaction to other amynoacylderivatives (prilocaine,bupivacaine) but not articaine.

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1981

ISSN: 0007-0912

DOI: 10.1093/bja/53.4.435